Author

A. P. Horton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

W. N. Voss· 3 shared D. R. Boutz· 2 shared G. C. Ippolito· 2 shared G. Georgiou· 2 shared J. D. Gollihar· 2 shared J. Goike· 2 shared J. R. McDaniel· 2 shared Y. Tanno· 2 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersImmunology

W. N. Voss

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Rapid characterization of spike variants via mammalian cell surface display

K. Javanmardi, C.-W. Chou, C. I. Terrace, A. Annapareddy, T. S. Kaoud, Q. Guo, J. Lutgens, H. Zorkic, A. P. Horton, E. C. Gardner, G. Nguyen, D. R. Boutz, J. Goike, W. N. Voss, H.-C. Kuo, , I. J. Finkelstein

This study characterizes SARS-CoV-2 spike variants by assessing their expression, ACE2 binding, and neutralizing antibody recognition across multiple variants.

bioRxiv · Mar 30, 2021Biochemistry

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma

W. N. Voss, Y. J. Hou, N. V. Johnson, J. E. Kim, G. Delidakis, A. P. Horton, F. Bartzoka, C. J. Paresi, Y. Tanno, S. A. Abbasi, W. Pickens, K. George, D. R. Boutz, D. M. Towers, J. R. McDaniel, , G. C. Ippolito

The paper identifies prevalent, protective, and convergent IgG antibodies targeting non-RBD epitopes of SARS-CoV-2 spike protein in convalescent plasma.

bioRxiv · Dec 20, 2020Immunology

Separating distinct structures of multiple macromolecular assemblies from cryo-EM projections

E. J. Verbeke, Y. Zhou, A. P. Horton, A. L. Mallam, D. W. Taylor, E. M. Marcotte

The paper develops a method to separate distinct macromolecular structures from heterogeneous cryo-EM data by using common lines in a graphical framework, enabling ab initio 3D structure reconstruction without stringent purification.

bioRxiv · Apr 30, 2019Biochemistry

Identification of Tumor-Reactive B Cells and Systemic IgG in Breast Cancer Based on Clonal Frequency in the Sentinel Lymph Node

J. R. McDaniel, S. C. Pero, W. N. Voss, G. S. Shukla, Y. Sun, S. Schaetzle, C.-H. Lee, A. P. Horton, S. Harlow, J. Gollihar, J. W. Ellefson, C. C. Krag, Y. Tanno, N. Sidiropoulos, G. Georgiou, , D. N. Krag

The paper identifies tumor-reactive B cells in sentinel lymph nodes and links them to systemic IgG antibodies in breast cancer patients using high-throughput sequencing and immunoproteomics.

bioRxiv · Nov 1, 2017Immunology