Single-cell analysis of pediatric acute myeloid leukemia samples uncovers treatment-resistant stem and mast cells
D. Ohlstrom, M. Bakhtia, H. Mumme, M. Michaud, F. Chien, W. Pilcher, S. Satpathy, S. Jordan, S. Bhasin, M. Bhasin
This study uses single-cell RNA sequencing to identify treatment-resistant subtypes and mast cell-like cells in pediatric AML, linking them to poor outcomes.
bioRxiv · Jul 9, 2024 · PreprintCancer Biology