Author

D. P. Frueh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

K. A. Marincin· 2 shared A. K. Kancherla· 1 shared D. J. Meyers· 1 shared D. P. Dowling· 1 shared E. S. Kengmana· 1 shared G. Bouvignies· 1 shared N. Sgourakis· 1 shared S. H. Mishra· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

K. A. Marincin

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2 papers

Recent·Most cited

NMR as a readout to monitor and restore the integrity of complex chemoenzymatic reactions

K. A. Marincin, Y. Hwang, E. S. Kengmana, D. J. Meyers, D. P. Frueh

This paper uses NMR to monitor and restore the integrity of a complex chemoenzymatic reaction by assessing reagent integrity and reaction progress.

bioRxiv · May 14, 2022Biophysics

Global Dynamics as Communication Sensors in Peptide Synthetase Cyclization Domains.

S. H. Mishra, A. K. Kancherla, K. A. Marincin, G. Bouvignies, S. Nerli, N. Sgourakis, D. P. Dowling, D. P. Frueh

The paper uses NMR to show that global dynamics in NRPS cyclization domains act as sensors for substrate interactions, enabling allosteric responses across the enzyme.

bioRxiv · Oct 6, 2021 · PreprintBiophysics