Author

D. Piktel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

J. Hollander· 1 shared K. Martin· 1 shared L. Gibson· 1 shared P. Saralkar· 1 shared P. Thomas· 1 shared Q. Hathaway· 1 shared R. R. Nair· 1 shared S. Rellick· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

J. Hollander

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1 paper

Recent·Most cited

Targeting the dysfunctional mitochondrial respiration in drug resistant B-cell acute lymphoblastic leukemia

R. R. Nair, D. Piktel, P. Thomas, Q. Hathaway, S. Rellick, P. Saralkar, K. Martin, W. J. Geldenhuys, J. Hollander, L. Gibson

This study identifies mitochondrial respiration dysfunction in drug-resistant ALL cells and shows that pyrvinium pamoate (PP) effectively targets this pathway, with enhanced bioavailability and specificity for leukemic cells.

bioRxiv · Apr 1, 2019 · PreprintCancer Biology