Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in an iPSC-derived air-liquid interface model
E. Schruf, V. Schroeder, H. Q. Le, T. Schoenberger, D. Raedel, E. L. Stewart, K. Fundel-Clemens, T. Bluhmki, S. Weigle, M. Schuler, M. J. Thomas, R. Heilker, M. J. Webster, M. Dass, M. Frick, , J. P. Garnett
This study develops an iPSC-derived air-liquid interface model to mimic IPF-related bronchiolization and shows IPF-RC stimulation alters ATII differentiation and transcriptome profiles.
bioRxiv · Nov 4, 2019Cell Biology