Ectoderm to mesoderm transition by downregulation of actomyosin contractility
L. Kashkooli, D. Rozema, L. Espejo-Ramirez, P. Lasko, F. Fagotto
The paper shows that differences in motility between ectoderm and mesoderm in Xenopus embryos are due to Rock-dependent actomyosin contractility, and that reducing this contractility can transform ectoderm into mesoderm-like cells.
bioRxiv · Oct 7, 2020Cell Biology