Shock drives a highly coordinated transcriptional and DNA methylation response in the endothelium
R. B. Ramos, N. Martino, D. S. Chuy, S. Lu, U. Balasubramanian, I. Di John Portela, P. A. Vincent, A. P. Adam
The paper investigates how shock-induced IL-6 signaling alters DNA methylation and transcription in endothelial cells, revealing a mechanism for sustained vascular dysfunction post-shock.
bioRxiv · Aug 1, 2022 · PreprintCell Biology