PIM Kinases Alter Mitochondrial Dynamics and Chemosensitivity in Lung Cancer
S. S. Chauhan, R. K. Toth, C. C. Jensen, A. L. Casillas, D. S. Kashatus, N. A. Warfel
This study shows that PIM kinase inhibition increases mitochondrial fission and ROS, enhancing chemotherapy sensitivity in NSCLC.
bioRxiv · Dec 5, 2019Cancer Biology