Imatinib mesylate induces necroptotic cell death and impairs autophagic flux in human cardiac progenitor cells
R. Walmsley, D. S. Steele, G. M. Ellison-Hughes, A. J. Smith
This study shows imatinib mesylate causes necroptotic cell death and impairs autophagy in human cardiac progenitor cells, with RIP1 inhibition reducing toxicity.
bioRxiv · Apr 12, 2021 · PreprintPharmacology & Toxicology