Author

D. Sag

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

D. G. Helvaci· 3 shared A. Korkmaz· 2 shared G. Wingender· 2 shared S. Gunalp· 2 shared Y. Dogan· 2 shared A. Bursali· 1 shared A. Cagir· 1 shared A. Conforte· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

D. G. Helvaci

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TRAIL promotes the polarization of human macrophages toward a proinflammatory M1 phenotype and is associated with increased survival in cancer patients with high tumor macrophage content

S. Gunalp, D. G. Helvaci, A. Oner, A. Bursali, A. Conforte, H. Guner, G. Karakulah, E. Szegezdi, D. Sag

bioRxiv · Aug 16, 2023 · PreprintImmunology

The Ca2+ concentration in vitro impacts the cytokine production of mouse and human lymphoid cells and the polarization of human macrophages

Y. C. Eskiocak, Z. O. Ayyildiz, S. Gunlap, A. Korkmaz, D. G. Helvaci, Y. Dogan, D. Sag, G. Wingender

This study shows that elevated Ca2+ concentrations enhance cytokine production in mouse and human lymphoid cells but increase cell death and promote M1 polarization in human macrophages.

bioRxiv · Aug 2, 2021Immunology

Astragalus Saponins, Astragaloside VII and Newly Synthesized Derivatives, Induce Dendritic Cell Maturation and T Cell Activation Through IL-1β Production

N. Yakubogullari, A. Cagir, E. Bedir, D. Sag

This study shows that AST VII and its derivatives enhance IL-1β production, leading to dendritic cell maturation and T cell activation in vitro.

bioRxiv · Jul 29, 2021 · PreprintImmunology

Effect of stimulation time on the expression of human macrophage polarization markers

D. Unuvar Purcu, A. Korkmaz, S. Gunalp, D. G. Helvaci, Y. Erdal, Y. Dogan, A. Suner, G. Wingender, D. Sag

This study determines the optimal stimulation times for analyzing human macrophage polarization markers in vitro, improving reproducibility and accuracy of experiments.

bioRxiv · Jul 26, 2021 · PreprintImmunology