Author

D. Santos-Martins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

S. Forli· 2 shared A. B. Ward· 1 shared B. E. Torbett· 1 shared C. M. Garza· 1 shared G. Ozorowski· 1 shared J. L. Torres· 1 shared M. Holcomb· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

S. Forli

Mutual co-authors in cluster

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2 papers

Recent·Most cited

IP6 and PF74 affect HIV-1 Capsid Stability through Modulation of Hexamer-Hexamer Tilt Angle Preference

C. M. Garza, M. Holcomb, D. Santos-Martins, B. E. Torbett, S. Forli

This study uses atomistic simulations to show how IP6 and PF74 modulate HIV-1 capsid stability by altering hexamer-hexamer tilt angles, revealing distinct effects on structural flexibility.

bioRxiv · Mar 11, 2024Biophysics

A strain-specific inhibitor of receptor-bound HIV-1 targets a pocket near the fusion peptide and offers a template for drug design

G. Ozorowski, J. L. Torres, D. Santos-Martins, S. Forli, A. B. Ward

The paper identifies a strain-specific HIV-1 inhibitor targeting a pocket near the fusion peptide, demonstrating small molecules can disrupt viral fusion and offering a template for drug design.

bioRxiv · Jun 11, 2020Biophysics