Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants
S. Rothenberger, D. L. Hurdiss, M. Walser, F. Malvezzi, J. Mayor, S. Ryter, H. Moreno, N. Liechti, A. Bosshart, C. Iss, V. Calabro, A. Cornelius, T. Hospodarsch, A. Neculcea, T. Looser, , Vassell
This paper describes ensovibep, a trispecific DARPin that inhibits SARS-CoV-2 variants by targeting the spike protein, showing potent antiviral activity and protection in animal models.
bioRxiv · Feb 3, 2021 · PreprintImmunology