Author

M. Walser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

A. Bosshart· 2 shared A. Cornelius· 2 shared A. Hajnal· 2 shared A. Neculcea· 2 shared A. Schlegel· 2 shared C. Iss· 2 shared C. Wang· 2 shared C. Zitt· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. Bosshart

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Author profile →

4 papers

Recent·Most cited

A DNA Replication-Independent Function of the pre-Replication Complex during Cell Invasion in C. elegans

E. Lattmann, T. Deng, M. Walser, P. Widmer, C. Rexha-Lambert, V. Prasad, O. Eichhoff, M. Daube, R. Dummer, M. Levesque, A. Hajnal

The paper identifies the pre-RC complex as a regulator of cell invasion in C. elegans, independent of its role in DNA replication.

bioRxiv · Jun 10, 2021 · PreprintCell Biology

Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants

S. Rothenberger, D. L. Hurdiss, M. Walser, F. Malvezzi, J. Mayor, S. Ryter, H. Moreno, N. Liechti, A. Bosshart, C. Iss, V. Calabro, A. Cornelius, T. Hospodarsch, A. Neculcea, T. Looser, , Vassell

This paper describes ensovibep, a trispecific DARPin that inhibits SARS-CoV-2 variants by targeting the spike protein, showing potent antiviral activity and protection in animal models.

bioRxiv · Feb 3, 2021 · PreprintImmunology

Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidates

M. Walser, S. Rothenberger, D. L. Hurdiss, A. Schlegel, V. Calabro, S. Fontaine, D. Villemagne, M. Paladino, T. Hospodarsch, A. Neculcea, A. Cornelius, P. Schildknecht, M. Matzner, M. Haenggi, M. Franchini, , Stittela

This paper develops potent anti-SARS-CoV-2 DARPin therapeutics with low picomolar neutralization efficacy and reports their protective efficacy in a hamster model.

bioRxiv · Aug 25, 2020 · PreprintImmunology

The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in C. elegans and human cells

A. Haag, M. Walser, A. Henggeler, A. Hajnal

This study shows that CHP-1 regulates EGFR trafficking and signaling in C. elegans and human cells, with HSP90-independent function and conserved effects on ER retention and MAPK signaling.

bioRxiv · Aug 25, 2019Cell Biology