The Endothelial Protein C Receptor plays an essential role in the maintenance of Pregnancy
M. M. Castillo, Q. Yang, A. Solis Sigala, D. T. McKinney, M. Zhan, K. L. Chen, J. A. Jarzembowski, R. Sood
This study shows that maternal thrombophilia, specifically through EPCR deficiency, leads to placental abruption and severe pregnancy complications, with potential therapeutic targets in thrombin-mediated platelet activation.
bioRxiv · Feb 5, 2020Physiology