A new mechanism of fibronectin fibril assembly revealed by live imaging and super-resolution microscopy.
D. Tomer, C. Arriagada, S. Munshi, B. Alexander, B. French, P. Vedula, V. Caorsi, A. House, M. Guvendiren, A. Kashina, J. Schwarzbauer, S. Astrof
This study reveals that Fn1 fibrils are composed of nanodomains rather than continuous fibers, using live imaging and SMLM to challenge the traditional view.
bioRxiv · Sep 9, 2020Cell Biology