Author

S. Astrof

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. House· 1 shared A. Kashina· 1 shared B. Alexander· 1 shared B. French· 1 shared C. Arriagada· 1 shared D. Sela-Donenfeld· 1 shared D. Tomer· 1 shared E. Nadjar-Boger· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. House

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Author profile →

2 papers

Recent·Most cited

Initiation of fibronectin fibrillogenesis is an enzyme-dependent process

S. Melamed, S. Zaffryar-Eilot, E. Nadjar-Boger, R. Aviram, H. Zhao, W. Yaseen-Badarne, R. Kalev-Altman, D. Sela-Donenfeld, O. Lewinson, S. Astrof, P. Hasson, H. Wolfenson

This study identifies fibronectin oxidation by lysyl-oxidase enzymes as a force-independent nucleation step initiating fibrillogenesis, which is critical for cell adhesion and mechanosensing.

bioRxiv · Nov 16, 2022Cell Biology

A new mechanism of fibronectin fibril assembly revealed by live imaging and super-resolution microscopy.

D. Tomer, C. Arriagada, S. Munshi, B. Alexander, B. French, P. Vedula, V. Caorsi, A. House, M. Guvendiren, A. Kashina, J. Schwarzbauer, S. Astrof

This study reveals that Fn1 fibrils are composed of nanodomains rather than continuous fibers, using live imaging and SMLM to challenge the traditional view.

bioRxiv · Sep 9, 2020Cell Biology