A systematic evaluation of IgM and IgG antibody assay accuracy in diagnosing acute Zika Virus infection in Brazil; lessons relevant to emerging infections
R. Medialdea-Carrera, F. Lowen Levy Chalhoub, P. Castanha, P. Carvalho Sequeira, P. Brasil, L. L. Lewis Ximenez, L. Turtle, T. Solomon, A. M. Bispo de Filippis, D. W. Brown, M. Griffiths
This study evaluates the accuracy of IgM and IgG antibody assays for diagnosing acute Zika Virus infection in Brazil, finding that IgG assays outperformed IgM ones and highlighting the need for careful evaluation in populations with co-circulating viruses.
bioRxiv · Nov 25, 2020Microbiology