Cancer BiologybioRxivPreprint
Grubraw, a chemogenetic mitochondrial activator, reveals new mechanisms underlying the Warburg effect
E. S. Potekhina, D. Y. Bass, A. V. Ivanenko…·V. Belousov
The paper introduces Grubraw, a chemogenetic tool that activates mitochondrial respiration in Warburg-type cancer cells, revealing that mitochondrial pyruvate export and reduced proliferation occur.
DOI 10.1101/2023.04.18.537329