Deletion of Nrf1 exacerbates oxidative stress-induced cellular senescence by disrupting the cell homeostasis
Da Lyu, Meng Wang, Lu Qiu, Rongzhen Deng, Shaofan Hu, Yiguo Zhang
This study shows that deleting Nrf1 increases oxidative stress-induced cellular senescence by disrupting homeostasis, as evidenced by increased senescence markers and impaired autophagy.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · Apr 23, 2025Peer-reviewedBiochemistry