Deletion of Nrf1α promotes glutamine addiction of HepG2 cells and thus enhances its apoptosis caused by glutamine deprivation
Rongzhen Deng, Qun Zhang, Keli Liu, Shaofan Hu, Reziyamu Wufuer, Xi Cheng, Da Lv, Yiguo Zhang
This study shows that deleting Nrf1α in HepG2 cells increases glutamine addiction and enhances cell death when glutamine is deprived.
bioRxiv · Mar 17, 2025 · PreprintBiochemistry