Estimating allele-specific expression of SNVs from 10x Genomics Single-Cell RNA-Sequencing Data
N. M. Prashant, Hongyu Liu, Pavlos Bousounis, Liam Flinn Spurr, Nawaf Alomran, Helen Ibeawuchi, Justin Sein, Dacian Reece-Stremtan, Anélia Horvath
The paper estimates allele-specific expression from 10x Genomics scRNA-seq data and finds that most SNVs are bi-allelic at higher read thresholds, with intronic SNVs showing more monoallelic expression.
Genes · Feb 25, 2020Peer-reviewedGenomics