Pavlos Bousounis

This study identifies KLF5-bound enhancers in pancreatic cancer that regulate cell survival, showing their subtype-independent role in maintaining tumor viability.

This study shows that cGAS-STING contributes to premature aging in telomerase-deficient zebrafish by promoting senescence and inflammation, and its absence rescues aging-related phenotypes.

SCReadCounts estimates cell-level SNVs from scRNA-seq data, enabling mutation analysis and downstream applications in cancer and other studies.

scReQTL correlates SNVs to gene expression in single-cell RNA-seq data by using variant allele fraction instead of population genotypes, enabling analysis of rare variants.

The paper estimates allele-specific expression from 10x Genomics scRNA-seq data and finds that most SNVs are bi-allelic at higher read thresholds, with intronic SNVs showing more monoallelic expression.

RsQTL identifies splicing quantitative trait loci by correlating variant allele fractions with splicing patterns in RNA-seq data from human tissues.

The paper introduces ReQTL, an eQTL analysis method using RNA genetic variation instead of DNA genotypes, showing high performance in identifying molecular associations from RNA-sequencing data.