Entamoeba histolytica Gal/GalNAc lectin intermediate subunit promotes inflammation and epithelial damage in intestinal amebiasis through its C3 region.
Hongze Zhang, Shaokun Pan, Meng Feng, Dai Dong, Yanqing Zhao, Ruixue Zhou, Wenjie Li, Xunjia Cheng
This study identifies the role of E. histolytica Igl in promoting inflammation and epithelial damage in intestinal amebiasis through its C3 region via TLR4/MyD88/NF-κB signaling.
bioRxiv · Apr 22, 2025 · PreprintMicrobiology