Harnessing Synaptic Vesicle Release and Recycling Mechanism for Molecule Delivery to Neurons
Karen Kar Lye Yee, Junichi Kumamoto, Daijiro Inomata, Naoki Suzuki, Ryuhei Harada, Norihiro Yumoto
This paper demonstrates a neuron-selective drug delivery system using synaptic vesicle release and recycling mechanism via anti-SYT2 antibodies to deliver therapeutic molecules to motor neurons.
bioRxiv · Sep 11, 2024 · PreprintNeuroscience