Static And Dynamic DNA Loops Form AP-1 Bound Activation Hubs During Macrophage Development
Douglas H. Phanstiel, Kevin Van Bortle, Damek V. Spacek, Gaelen T. Hess, Muhammad S. Shamim, Ido Machol, Michael I. Love, Erez Lieberman Aiden, Michael Cory Bassik, Michael P. Snyder
The paper identifies multi-loop activation hubs during macrophage development using Hi-C data, showing they are enriched for AP-1 binding and driven by cell-type specific transcription factors.
Molecular Cell · Sep 1, 2017Peer-reviewedGenomics