Author

Dan Heiter

New England Biolabs (United States)

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Genomics· 1

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

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Jim Samuelson· 1 shared Laurence M. EttwilleriD· 1 shared Lixin CheniD· 1 shared Minyong CheniD· 1 shared Tom Evans· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperGenomics

Jim Samuelson

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1 paper

Recent·Most cited

FFPE DNA shows two major error profiles derived from deamination of cytosine and methylcytosine that can be mitigated using distinct repair strategies.

Lixin Chen, Minyong Chen, Dan Heiter, Jim Samuelson, Tom Evans, Laurence M. Ettwiller

The paper identifies two distinct error profiles in FFPE DNA caused by cytosine and methylcytosine deamination and shows how specific repair strategies can mitigate these errors.

bioRxiv · Mar 2, 2023 · PreprintGenomics