Human genetic variation shapes the response of neurons to interferons
Milena M. Andzelm, Sonia Bolshakova, Noah L. Pettinari, Matthew Tegtmeyer, Dan Meyer, Autumn Johnson, Curtis J. Mello, Chang Yu, Ilinca Mazureac, Giulio Genovese, Adrianna Maglieri, Kiku Ichihara, Marina Hogan, Derek Hawes, Steven A. McCarroll, Ralda Nehme
The paper identifies genetic variants that influence neuronal responses to interferons by analyzing gene expression and STAT1 binding in iPSC-derived neurons.
bioRxiv · May 28, 2025 · PreprintMolecular Biology