CELF2 promotes tau exon 10 inclusion via hinge domain-mediated nuclear condensation
Xin Li, Ishana N. Syed, Zhao Zhang, Rashmi Adhikari, Dan Tang, Su Hyuk Ko, Zhijie Liu, Lizhen Chen
This study shows CELF2 regulates Tau exon 10 inclusion via IDR-mediated nuclear condensation with NOVA2 and SFPQ, affecting the 4R:3R ratio in mice.
bioRxiv · Nov 2, 2024 · PreprintMolecular Biology