Elevation of the mechanically-sensitive protein emerin links nuclear mechanotransduction to tau-induced cytoskeletal remodeling in neurons
Claira Sohn, Sammy Pardo, Dana Molleur, Satvik R Paduri, Morgan Lambert, Zachary Uttke, Erich J. Sohn, Morgan G. Thomas, Susan T. Weintraub, Bess E Frost
This study identifies emerin as a mediator of cytoskeletal remodeling in tauopathy by showing its elevation and relocalization in neuronal models of tauopathy, linking nuclear mechanotransduction to neurotoxicity.
Nucleus · Jul 7, 2026Peer-reviewedCell Biology