Author

Dandan Zheng

State Key Laboratory of OphthalmologyPrimary ORCID profile (0000-0003-2259-1633 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Dandan ZhengiD1 paper · University of Rochester Medicine

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Fuying Guo· 2 shared Guanjie Gao· 2 shared Ping XuiD· 2 shared Suai Zhang· 2 shared Xiaojing SongiD· 2 shared Xiufeng ZhongiD· 2 shared Yuan WangiD· 2 shared Bella Y. Luo· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Fuying Guo

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Author profile →

2 papers

Recent·Most cited

Exogenous Photoreceptor-Specific N-Glycosylated PROM1 Rescues Retinal Degeneration in Patient and Mouse Models

Ping Xu, Fuying Guo, Yuan Wang, Guifu Chen, Xiaojing Song, Bella Y. Luo, Dandan Zheng, Guanjie Gao, Wenjing Yin, Suai Zhang, Bruce T. Lahn, Xiufeng Zhong

This study demonstrates that gene therapy using AAV vectors can rescue retinal degeneration in PROM1-IRD patient and mouse models by restoring PROM1 expression and photoreceptor structure.

Molecular Therapy · Feb 27, 2026Peer-reviewedNeuroscience

Longitudinal analysis of retinal cell state transitions in RB1-deficient retinal organoids reveals the nascent cone precursors are the earliest cell-origin of human retinoblastoma

Ke Ye, Yuan Wang, Ping Xu, Bingbing Xie, Shijing Wu, Wenxin Zhang, Guanjie Gao, Dandan Zheng, Xiaojing Song, Suai Zhang, Fuying Guo, Yongping Li, Yizhi Liu, Jie Wang, Ruifang Sui, Xiufeng Zhong

This study identifies ATOH7+ nascent cone precursors as the earliest cell-of-origin for human retinoblastoma using RB1-deficient retinal organoids and scRNA-seq.

Cell Death and Disease · Jan 14, 2026Peer-reviewedCell Biology