Yizhi Liu

This study identifies ATOH7+ nascent cone precursors as the earliest cell-of-origin for human retinoblastoma using RB1-deficient retinal organoids and scRNA-seq.

The paper identifies and analyzes nonreference sequences in human genomes using long-read sequencing and graph-based pangenome methods, revealing their functional, evolutionary, and phenotypic significance.

This study shows that m6A modification regulates the transition from retinal progenitor cells to glial cells, affecting retinal development and function.

Falign improves alignment of fragmented long noisy 3C data by addressing fragment boundary issues and increasing data utilization.

The paper performs long-read sequencing in 405 Chinese individuals to discover and characterize structural variants, finding novel SVs and their associations with phenotypes and diseases.

HIT-scISOseq improves single-cell isoform sequencing throughput and accuracy, revealing novel transcriptomic features in corneal epithelium injury.

NECAT improves Nanopore read error correction and de novo assembly, achieving higher accuracy and faster performance for genome assembly.

scCAT-seq identifies and quantifies single-cell RNA isoforms using short-read sequencing, revealing novel transcripts and cell-type specific isoforms in DRG neurons and oocytes.