Human RAP2A Homolog of the Drosophila Asymmetric Cell Division Regulator Rap2l Targets the Stemness of Glioblastoma Stem Cells
Maribel Franco, Ricardo Gargini, Víctor Manuel Barberá, Daniel Becerra, Miguel Saceda, Ana Carmena
This study identifies RAP2A as a regulator of asymmetric cell division in glioblastoma stem cells, showing its loss correlates with poor prognosis and its restoration reduces stemness and proliferation.
eLife · Nov 28, 2025Peer-reviewedCancer Biology