Author

Miguel Saceda

Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat ValencianaORCID 0000-0002-1564-3602Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana CarmenaiD· 1 shared Camino de Juan Romero· 1 shared Daniel Becerra· 1 shared Elizabeth Pérez-ValencianoiD· 1 shared José Antonio EncinariD· 1 shared Laura Fuertes-García· 1 shared María Fuentes-BaileiD· 1 shared Maribel Franco· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Ana CarmenaORCID

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2 papers

Recent·Most cited

Targeting the CDK4-Cyclin D Complex: A New Generation of Selective Kinase Inhibitors for Cancer Therapy

María Fuentes-Baile, José Antonio Encinar, Salomé Araujo‐Abad, Elizabeth Pérez-Valenciano, Pilar García-Morales, Laura Fuertes-García, Camino de Juan Romero, Miguel Saceda

This paper identifies a novel CDK4 inhibitor, diophenic, that selectively targets the CDK4-Cyclin D1 interaction, showing improved selectivity and reduced off-target effects compared to ATP-competitive inhibitors in GBM models.

bioRxiv · Sep 22, 2026 · PreprintCancer Biology

Human RAP2A Homolog of the Drosophila Asymmetric Cell Division Regulator Rap2l Targets the Stemness of Glioblastoma Stem Cells

Maribel Franco, Ricardo Gargini, Víctor Manuel Barberá, Daniel Becerra, Miguel Saceda, Ana Carmena

This study identifies RAP2A as a regulator of asymmetric cell division in glioblastoma stem cells, showing its loss correlates with poor prognosis and its restoration reduces stemness and proliferation.

eLife · Nov 28, 2025Peer-reviewedCancer Biology