Mitochondrial organization in the developing proximal tubule is controlled by LRRK2
Mohsina Khan, Kyle Bond, Elyse D. Grilli, Daniel Cameron, Liyang Zhao, Sunder Sims‐Lucas, Andrew P. McMahon, Thomas J. Carroll, Leif H. Oxburgh
This study shows that mitochondrial redistribution in developing proximal tubule cells depends on fluid flow and LRRK2 activity, which is regulated by shear stress.
Nature Communications · Oct 30, 2025Peer-reviewedDevelopmental Biology