Metabolite correlation networks reveal complex phenotypes of adaptation-driving mutations
Sharon Samuel, Weronika Jasińska, Ezra Sternlicht, Matvey I. Nikelshparg, Daniel Kleiner, Shai Pilosof, Shimon Bershtein
The paper shows that adaptive mutations in E. coli alter metabolite correlation networks, improving fitness through network rewiring without directly affecting SAM metabolism.
Nature Communications · Sep 16, 2026Peer-reviewedEvolutionary Biology