3D spatial distribution of Sost mRNA and Sclerostin expression in response to in vivo mechanical loading
Quentin A Meslier, Jacy Hoffmann, Robert Oehrlein, Daniel Kurczy, James R. Monaghan, Sandra J. Shefelbine
This study uses WISH-BONE to analyze 3D Sost mRNA and sclerostin distribution in mouse tibia midshafts after mechanical loading, showing region-specific changes and highlighting the method's importance for mechanoadaptation research.
Bone · Feb 18, 2025Peer-reviewedBioengineering