Minipuberty regulates reproductive lifespan and ovarian follicular loss in a mouse model with reduced minipubertal gonadotropin levels
Mélanie Chester, Marie M. Devillers, Raphaël Corre, Frank Giton, Fatoumata Souaré, Claire-Hélène Petrovic, Éloïse Airaud, Daniel Quintas, Sakina Mhaouty‐Kodja, Lydie Naulé, Céline Julie Guigon
This study shows that reducing minipubertal gonadotropin levels in mice extends reproductive lifespan but accelerates ovarian follicle depletion without affecting early fertility.
Human Reproduction · Feb 13, 2025Peer-reviewedPhysiology