Author

Mélanie Chester

Centre National de la Recherche ScientifiqueORCID 0009-0004-3316-9387Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

Céline Julie GuigoniD· 2 shared Frank GitoniD· 2 shared Aminé Isik· 1 shared Audrey Der VartanianiD· 1 shared Céline HéraudiD· 1 shared Chantal MathisiD· 1 shared Claire-Hélène Petrovic· 1 shared Daniel Quintas· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

Céline Julie GuigonORCID

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2 papers

Recent·Most cited

Mass Spectrometry-Based Profiling of Deuterium-Labeled Sex Steroids Enables Non-Invasive Mapping of Steroid Dynamics in Intact Mice

Frank Giton, Audrey Der Vartanian, N. Wyckens, Ioana Ferecatu, Mélanie Chester, Céline Héraud, Aminé Isik, Chantal Mathis, Céline Julie Guigon

This paper develops a mass spectrometry-based method to track steroid dynamics in intact mice, revealing tissue-specific metabolism patterns of sex steroids.

bioRxiv · Sep 9, 2026 · PreprintBiochemistry

Minipuberty regulates reproductive lifespan and ovarian follicular loss in a mouse model with reduced minipubertal gonadotropin levels

Mélanie Chester, Marie M. Devillers, Raphaël Corre, Frank Giton, Fatoumata Souaré, Claire-Hélène Petrovic, Éloïse Airaud, Daniel Quintas, Sakina Mhaouty‐Kodja, Lydie Naulé, Céline Julie Guigon

This study shows that reducing minipubertal gonadotropin levels in mice extends reproductive lifespan but accelerates ovarian follicle depletion without affecting early fertility.

Human Reproduction · Feb 13, 2025Peer-reviewedPhysiology