An extracellular substrate for the temporary storage of memories
Ricardo Guajardo, Ashley N. Starnes, Supriya M Mula, Dong Kyu Kim, Maxwell Bennett, Ran Cao, Daniel Yuan, Miray Girguis, Ling Wu, Hongfei Xu, L. Ferrari, Violeta Durán Laforet, Erica J. Stevenson, Dorothy P. Schafer, Nevan J. Krogan, , Anna Victoria Molofsky
The paper identifies aggrecan as an extracellular matrix protein that stabilizes fear memories by altering neuronal excitability in the hippocampal dentate gyrus.
bioRxiv · Oct 24, 2026 · PreprintNeuroscience