NKX2.1 is critical for melanocortin neuron identity, hypothalamic Pomc expression and body weight
Daniela P. Orquera, María B. Tavella, Flávio S. J. de Souza, Sofía Nasif, Malcolm James Low, Marcelo Rubinstein
This study shows that NKX2.1 is essential for Pomc expression in hypothalamic neurons and body weight regulation through its role in enhancer activity.
bioRxiv · Nov 4, 2018 · PreprintGenetics