Author

Malcolm James Low

University of MichiganORCID 0000-0002-9900-3708Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aliyu Jabir Muhammad· 1 shared Amanda Lea SharpeiD· 1 shared Berkan KanmaziD· 1 shared Chun‐Xia YiiD· 1 shared Daniel Hüebschmann· 1 shared Daniel N. KazdaliD· 1 shared Daniela P. Orquera· 1 shared Derya S. Arslan· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Aliyu Jabir Muhammad

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 30, 2026

Magel2 deficiency drives microglial synaptic engulfment and alters neuron-microglia interactions in Prader-Willi syndrome

Jemima Helen, Moritz Claudius Wimmer, Berkan Kanmaz…·Ferdinand Althammer

This study shows that Magel2 deficiency in a mouse model of Prader-Willi syndrome causes microglial structural changes and increased synaptic engulfment, altering neuron-microglia interactions and hypothalamic circuit function.

DOI 10.64898/2026.09.30.755583

mousebulk RNA-seq

NeurosciencebioRxivApr 13, 2022

Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food

Nicole L. Eliason, Lynne Martin, Malcolm James Low, Amanda Lea Sharpe

This study shows that melanotan-II injected into the nucleus accumbens reduces food consumption and appetitive behavior without affecting metabolism or causing aversion.

7 citations

mouseexperimental assay

GeneticsbioRxivPreprintNov 4, 2018

NKX2.1 is critical for melanocortin neuron identity, hypothalamic Pomc expression and body weight

Daniela P. Orquera, María B. Tavella, Flávio S. J. de Souza…·Marcelo Rubinstein

This study shows that NKX2.1 is essential for Pomc expression in hypothalamic neurons and body weight regulation through its role in enhancer activity.

DOI 10.1101/460501

mousestatistical model