A tale of two tails - efficient profiling of protein degraders by specific functional and target engagement readouts
Alexey L. Chernobrovkin, Cindy Cázares-Körner, Tomas Friman, Isabel Martín Caballero, Daniele Amadio, Daniel Martinez Molina
The paper profiles protein degraders using CETSA MS to assess target engagement and degradation efficacy in intact cells.
SLAS DISCOVERY · Jan 15, 2021Peer-reviewedMolecular Biology