Pleotropic effects of PPARD accelerate colorectal tumor progression and invasion
Yi Liu, Yasunori Deguchi, Rui Tian, Daoyan Wei, Weidong Chen, Min Xu, Ling Wu, Fuyao Liu, Shen Gao, Jonathan C. Jaoude, Sarah P. Chrieki, Micheline J. Moussalli, Mihai Gagea, Jeffrey S. Morris, Russell Broaddus, , Imad Shureiqi
This study shows that PPARD promotes colorectal cancer progression and invasion by enhancing β-catenin signaling and multiple pro-invasive pathways.
bioRxiv · May 24, 2018 · PreprintCancer Biology