PPARD regulation in gastric progenitor cells drives gastric tumorigenesis in mice
Xiangsheng Zuo, Yasunori Deguchi, Weiguo Xu, Daoyan Wei, Rui Tian, Weidong Chen, Micheline J. Moussalli, Yi Liu, Fei Mao, Min Xu, Yaying Yang, Shen Gao, Jonathan C. Jaoude, Fuyao Liu, Mihai Gagea, , Imad Shureiqi
This study shows that PPARD overexpression in gastric progenitor cells drives gastric tumorigenesis in mice by promoting inflammation, self-renewal, and tumorigenic properties.
bioRxiv · Nov 12, 2017 · PreprintCancer Biology