Author

Darin D. Vaughan

University of Kentucky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Peter Michael Kekenes-HuskeyiD· 2 shared Adam D. BachstetteriD· 1 shared Bin SuniD· 1 shared Bradley D. Stewart· 1 shared Byeong Jae ChuniD· 1 shared Jonathan P. DavisiD· 1 shared Svetlana Tikunova· 1 shared Trevor P. CreameriD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

Peter Michael Kekenes-HuskeyORCID

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2 papers

Recent·Most cited

Molecular basis of calmodulin-dependent calcineurin activation

Bin Sun, Darin D. Vaughan, Svetlana Tikunova, Trevor P. Creamer, Jonathan P. Davis, Peter Michael Kekenes-Huskey

This study identifies a secondary CaM binding site on calcineurin that contributes to its activation through molecular simulations and mutagenesis experiments.

Biophysical Journal · Feb 1, 2019Peer-reviewedMolecular Biology

Simulation of P2X-mediated calcium signaling in microglia

Byeong Jae Chun, Bradley D. Stewart, Darin D. Vaughan, Adam D. Bachstetter, Peter Michael Kekenes-Huskey

The paper develops a computational model to simulate P2X-mediated calcium signaling in microglia and quantifies TNF production under various ATP stimulation conditions.

The Journal of Physiology · Nov 21, 2018Peer-reviewedSystems Biology