Author

Jonathan P. Davis

The Ohio State UniversityORCID 0000-0002-5627-1550Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 2 Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Peter Michael Kekenes-HuskeyiD· 2 shared Aleksei Chekodanov· 1 shared Bin SuniD· 1 shared Björn C. KnollmanniD· 1 shared Christopher N. JohnsoniD· 1 shared Daniel J. BlackwelliD· 1 shared Darin D. Vaughan· 1 shared Md Nure Alam AfsariD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

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10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Peter Michael Kekenes-HuskeyORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintApr 17, 2026

Dynamic-Structure Redesign of Calmodulin Reveals Mechanistic Constraints on Ryr2 Regulation

Vladimir Bogdanov, Svetlana B. Tikunova, Nicolas Fadell…·Jonathan P. Davis

The paper redesigns calmodulin to improve its function while preserving conformational dynamics, showing that structural flexibility is essential for physiological regulation.

DOI 10.64898/2026.04.14.717973

humanprotein structure

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Molecular BiologyBiophysical JournalPeer-reviewedFeb 1, 2019

Molecular basis of calmodulin-dependent calcineurin activation

Bin Sun, Darin D. Vaughan, Svetlana Tikunova…·Peter Michael Kekenes-Huskey

This study identifies a secondary CaM binding site on calcineurin that contributes to its activation through molecular simulations and mutagenesis experiments.

DOI 10.1016/j.bpj.2018.11.1808

statistical model

𝕏 PostBluesky