Bin Sun

This study shows that myristoylation of VP4 enables membrane anchoring, phase separation, and pore formation in enteroviruses through multiple functional roles.

This study shows that protein-protein interactions can follow static or dynamic binding paradigms, with distinct temperature dependencies and mechanisms affecting affinity prediction.

The paper reviews Brownian dynamics modeling of biomolecular binding and its integration with machine learning for predicting in vivo kinetics.

This study shows that pathogenic missense mutations affect Menin function through dynamic changes and allostery, not just structural destabilization.

This study shows that the disordered JM motif in RTKs dynamically influences DFGout conformation formation, promoting classical conformations favorable for inhibitor binding.

This study investigates how phosphorylation of ABLIM1's intrinsically disordered regions modulates its interaction with titin, affecting cardiac muscle contraction.

This study identifies a secondary CaM binding site on calcineurin that contributes to its activation through molecular simulations and mutagenesis experiments.