Author

Darren C. H. Chan

University of Toronto

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Bioinformatics· 1

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:spatial transcriptomics· 1

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Alina SelegaiD· 1 shared Anuroopa DineshiD· 1 shared Conor KlamanniD· 1 shared Edward L.Y. CheniD· 1 shared Hartland Warren JacksoniD· 1 shared Kieran R. CampbelliD· 1 shared Miralem MrkonjiciD· 1 shared Somaieh Afiuni‐ZadehiD· 1 shared

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Alina SelegaORCID

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1 paper

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedJan 4, 2025

Segmentation aware probabilistic phenotyping of single-cell spatial protein expression data

Yu‐Ju Lee, Edward L.Y. Chen, Darren C. H. Chan…·Kieran R. Campbell

STARLING quantifies cell populations from spatial protein expression data while accounting for segmentation errors, identifying known cell types and quantifying heterogeneity in human tonsil tissue.

13 citations

humanspatial transcriptomics

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