Author

Edward L.Y. Chen

Lunenfeld-Tanenbaum Research InstituteORCID 0000-0001-7197-2243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Hartland Warren JacksoniD· 2 shared Kieran R. CampbelliD· 2 shared Alina SelegaiD· 1 shared Anuroopa DineshiD· 1 shared Caroline DiorioiD· 1 shared Conor KlamanniD· 1 shared Darren C. H. Chan· 1 shared Golnaz Abazari· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioinformatics

Hartland Warren JacksonORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 15, 2025

Rakaia: interactive discovery of spatial biology at scale

Matthew Watson, Golnaz Abazari, Edward L.Y. Chen…·Hartland Warren Jackson

Rakaia enables interactive exploration of spatial biology data through a browser-based platform, identifying cell types in non-malignant human breast tissue.

DOI 10.1101/2025.08.15.670550

humanspatial transcriptomics

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BioinformaticsNature CommunicationsPeer-reviewedJan 4, 2025

Segmentation aware probabilistic phenotyping of single-cell spatial protein expression data

Yu‐Ju Lee, Edward L.Y. Chen, Darren C. H. Chan…·Kieran R. Campbell

STARLING quantifies cell populations from spatial protein expression data while accounting for segmentation errors, identifying known cell types and quantifying heterogeneity in human tonsil tissue.

13 citations

humanspatial transcriptomics

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Developmental BiologyDevelopmentPeer-reviewedJan 1, 2020

NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development

Jie Li, Julie Gordon, Edward L.Y. Chen…·Nancy Ruth Manley

This study shows Notch1 signaling is essential for specifying and expanding the medullary thymic epithelial cell (mTEC) progenitor pool during mouse fetal development.

31 citations

mouseexperimental assay

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