In vitro effects of selected angiogenesis-promoting drugs on human Ea.hy926 endothelial cells treated with critical-stage dengue hemorrhagic fever serum
Nipuni Chandrasiri, Maheshi Mapalagamage, Hansani Gunasekara, Darshan De Silva, Gayani Premawansa, Shiroma Mangalika Handunnetti, Sunil Premawansa
This study evaluates the effects of Simvastatin, Phenytoin, and Ascorbic acid on endothelial dysfunction in Ea.hy926 cells treated with DHF serum, finding that low-dose Simvastatin reduces cell-cell distances and increases cell size.
bioRxiv · Sep 19, 2025 · PreprintImmunology